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Understanding the Gut-Brain Connection for Holistic Wellbeing
Imagine waking up with constant fatigue, mood swings, or anxiety—and your doctor says, “Let’s start by looking at your gut.” Surprising? You’re not alone. Many people are unaware that their mental health could be directly linked to what’s happening in their digestive system. Lets explore how your gut might be the missing piece in your mental wellness journey.
Our gut is often called the “second brain” for a good reason. Known medically as the gut-brain axis, this communication system links the emotional and cognitive centres of the brain with intestinal functions. The vagus nerve, hormonal pathways, and immune signals form this powerful two-way street.
In fact, about 90% of serotonin—a key neurotransmitter affecting mood, appetite, and sleep—is produced in the gut, not the brain (Johns Hopkins Medicine, 2023). When your digestive system is inflamed, sluggish, or imbalanced, your mind feels it.
This link has changed the conversation around mental health. Rather than focusing only on the brain, healthcare providers are taking a more holistic approach that includes gastrointestinal health. Addressing gut issues could be the turning point for those struggling with emotional instability.
Poor digestion is not just a physical issue—it can be a mental health red flag. Recent data published in Frontiers in Psychiatry (2023) show that people with chronic gastrointestinal symptoms are twice as likely to suffer from anxiety and depression compared to those without digestive issues.
When your gut is healthy, it communicates positive signals to your brain. When it’s not, the message is distorted, leading to symptoms like low mood, irritability, brain fog, and fatigue.
The impact is profound and often underestimated. Many people spend years treating emotional symptoms with medication alone, unaware that supporting their digestive system might lead to greater mental stability. It’s a classic case of treating the branches instead of nurturing the roots.
At the heart of this connection is your gut microbiome—the vast ecosystem of bacteria, fungi, and other microbes living in your intestines. A balanced microbiome supports digestion, regulates inflammation, and contributes to hormone production.
However, stress, processed foods, antibiotics, and lack of sleep can throw off this delicate balance, leading to gut dysbiosis—a condition closely linked with mood disorders.
The diversity and richness of your gut microbiome can determine how resilient you are to mental stress. A robust microbiome acts as a protective shield, reducing the risk of neurological and emotional imbalances over time.
Several common digestive issues can influence your psychological state:
IBS isn’t just uncomfortable—it’s emotionally exhausting. Studies have shown that up to 70% of individuals with IBS experience anxiety or depression (NHS, 2023).
While still under research, increased intestinal permeability may allow toxins into the bloodstream, triggering inflammation that affects the brain’s functioning.
Persistent irregular bowel movements can worsen stress levels, interfere with social life, and even trigger panic symptoms.
Nutrition plays a vital role in gut and mental health. Enter probiotics and prebiotics—two unsung heroes of wellness.
Probiotics for mental wellness are live microorganisms that, when consumed in adequate amounts, offer health benefits. A 2023 meta-analysis in Nutritional Neuroscience found that probiotics significantly reduce symptoms of depression and anxiety in adults.
Common sources include:
Prebiotics are dietary fibres that feed the good bacteria in your gut. Think of them as the soil to your gut’s garden. Foods like garlic, onions, bananas, and oats help nourish your microbiome, promoting better mental clarity and emotional stability.
If you’re looking to make sustainable lifestyle changes, here are practical, science-backed tips:
Eating more vegetables, whole grains, legumes, and nuts supports microbiome diversity.
High-sugar, high-fat foods disrupt gut bacteria and fuel inflammation—both linked to anxiety and depression.
Regular physical activity not only boosts your mood but also improves gut motility and microbiome diversity.
Techniques like yoga, journaling, deep breathing, and mindfulness can reduce gut inflammation and calm the brain.
Poor sleep disrupts your gut-brain connection, leading to a vicious cycle of stress and indigestion.
The idea that your mental health might start in your stomach is no longer radical—it’s science. Addressing gut health is not a quick fix for emotional wellness, but it’s a powerful tool in a holistic care plan.
At Parul Sevashram Hospital, our multidisciplinary approach—combining gastroenterology and mental wellness services—ensures that patients are treated with empathy and evidence-based care. We believe that understanding the gut-brain connection is key to healing both body and mind.
If you’re struggling with chronic gut issues or emotional distress, our expert teams in the Gastroenterology departments are here to help you start your journey to better health.
Written by Parul Sevashram Hospital | 8 April 2025
Dr. Jagdish T. Gohil is the Dean at Parul Institute of Medical Sciences & Research. He has a vast experience of over 37 years in Obstetrics & Gynecology. He is an alumnus of Baroda Medical College. He has worked at the Government Medical College & SSG Hospital, Baroda in various capacities since 1988. He has been a UG & PG examiner at various universities in the country He is well known gynecologist has conducted many complicated surgeries during his tenure as Associate Professor at SSG Hospital, Baroda and still continues to do in spite of being the post of Dean. He has guided more than 30 PG students also more than 5 PhD. Scholars for their research. He has been an assessor for Medical facilities for the MCI at Medical Colleges & Hospitals. He has been a member of the PG council at the M.S. University of Baroda. He is life member of Indian Medical Association, Indian Association of Gynec Endoscopy, Life Member and Indian Menopause Society, life member of Indian Association of Gynec Oncology. He is active member of FOGSI since last 30 years. He had delivered many lectures in State and National Conferences.
M. No. : +91 9825151528
Email : medicaldean@paruluniversity.ac.in
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Dr. Dipesh Duttaroy holds more than 38 years of rich and vast experience in General Surgery and currently serves as the Director – Post Graduate Studies and Professor in the Department of General Surgery at Parul Institute of Medical Science & Research. He superannuated as Professor and Head of the Department of Surgery at Medical College Baroda and has previously served at Government Medical College Surat and M.P. Shah Medical College Jamnagar. He was also Dean of Students for the Faculty of Medicine at The Maharaja Sayajirao University of Baroda and has guided over 50 postgraduate students in General Surgery.
As a former member of the Ethics Committee of the Medical Council of India and a current ethics committee member at HMPCMCE Karamsad and IECHR Medical College Baroda, Dr. Duttaroy is a recognized subject expert. He has served on selection boards for the UPSC and GPSC, as an examiner at various universities and the National Board of Examinations, and as an assessor for accreditation of medical facilities for both MCI and NBE.
Dr. Ekta Modi represents Parul Sevashram Hospital as Chief Operating Officer. With a vast experience of over 18 years, she is an expert in the fields of administration, quality, branding, and marketing, all while maintaining a patient-centric approach. She holds a Doctorate in Management Studies along with an MBA in Healthcare Management and has completed Management Development Programs (MDP) at IIM Ahmedabad and AIIMS Delhi.
Dr. Atul Kumar Saxena is a Medical Superintendent at Parul Institute of Medical Science & Research. Dr. A.K. Saxena brings to PSH a vast surgical experience of over 35 years in General Surgery. He is an alumnus of Baroda Medical College. He has worked at the Government Medical College & SSG Hospital, Baroda in various capacities since 1981. He has handled administrative duties as Medical Superintendent of 1500-bed SSG Hospital, Baroda, Additional Dean of Baroda Medical College and Head of the Emergency Medicine Dept. He established the Department of Emergency Medicine at Baroda Medical College offering an MCI-recognised MD programme in EM. He has been on the selection boards of the UPSC & GPSC as a subject expert. He has been a UG & PG examiner at various universities across India and the NBE for both General Surgery & EM. He has guided more than 45 PG students in their research. He has assessed medical facilities for the MCI and NBE and served as a member of the Senate and PG Council at M.S. University of Baroda.
M. No.: 9825177292
Email: atulkumar.saxena77687@paruluniversity.ac.in
Dr.Devanshu Patel, a dynamic, visionary and proactive leader, is President of Parul University. His unflinching commitment to the cause of education and whose continuous efforts for spreading the cause of education not only in Gujarat but also in different states of India and also in 49 different countries have resulted in more than 25,000 students pursuing their undergraduate, post graduate and doctoral degree programmes in 34 academic institutions offering more than 160 degree programmes.
Dr.Komal Patel serves as Member of the Governing Body in the University and Director. She’s an eminent laparoscopic surgeon, Gold medalist in Obstetrics and Gynaecology, as well as overseeing the smooth functioning of the Department in Parul Sevashram Hospital. She is actively involved in establishing and developing surgical departments in Parul Sevashram Hospital. She had worked as a Gynaecologist and Obstetrician in Parul Maternity Home in Baroda prior to joining Parul University.
Dr Geetika Madan Patel is a proficient doctor and administrator having pursued her MBBS and MD in Community Medicine with Gold Medal from the illustrious Maharaja Sayajirao University of Baroda. Currently she is the Member of Board of Governance and Medical Director of Parul University. She has played key role in the establishment of various medical institutions & hospitals in Parul University and is now heading Parul Sevashram Hospital.
Dr. Mrs. Kalpana R. Sulhyan is the Dean at Parul Institute of Medical Science & Research. She has teaching experience of over 34 years. She was selected as Professor of Pathology by Maharashtra Public Service Commission in 2000 and she has worked as Professor & Head of Pathology department in various Government Medical Colleges in Maharashtra State. She retired from Maharashtra State Department of Medical Education and Research on 31st August, 2019. She was recognized PG Teacher of Maharashtra University of Health Sciences and was PG Teacher for more than 80 PG Students of Pathology. In her guidance, Department of Pathology of GMC, Miraj received histopathological excellence award at state level many times. She has 65 National & International Publications. She was appointed by Maharashtra State Government as Officer on Special Duty for development of three new Government Medical Colleges at Latur, Akola and Kolhapur. She has worked as Assessor of Medical Council of India for many Medical Colleges for both undergraduate and postgraduate courses. She has worked as Dean of Government Medical College. She was selected as Dean by Maharashtra Public Service Commission.
M. No. : +91 9552012233
Email : medicaldean@paruluniversity.ac.in
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